mots-c peptide

MOTS-c is a mitochondrial-derived peptide (MDP), a 16-amino-acid protein encoded in the mitochondrial genome, that regulates metabolic homeostasis. It improves glucose metabolism, enhances exercise endurance, and prevents age- and diet-related insulin resistance and obesity. MOTS-c acts by translocating to the nucleus, where it activates the AMPK pathway to regulate gene expression, thereby promoting cellular balance. While showing promise for treating metabolic and age-related diseases, MOTS-c is not approved for human use, and potential side effects like increased heart rate, insomnia, and fever have been reported by those using unauthorized online